The 27-year-old Belgium international had joined City squad last week after helping his country progress to the World Cup semi-finals in Russia.
Chelsea parted ways with Enzo Maresca on Thursday, a dramatic fall from grace for the Italian who was named manager of the month for November before the club won just one of their last seven league games to fall out of the Premier League title race.
Crystal Palace's Eberechi Eze sparked a massive south London party by scoring the only goal to win the FA Cup 1-0 against Manchester City on Saturday and claim the club's first major trophy in their history.
Manchester City emerged from a trough of despair to beat Tottenham Hotspur 3-1 and move to within three points of the Premier League title at Wembley on Saturday.
Kyle Walker hung up his England boots on Tuesday, four matches shy of a landmark 100 caps, bringing the curtain down on a 14-year international career that saw him twice finish as a European Championship runner-up.
Manchester City are at risk of missing out on next season's Champions League due to their recent dip in form, manager Pep Guardiola said.
Celtic manager Brendan Rodgers has a goalkeeping dilemma to resolve before ManchesterCity turn up for their Group C Champions League match in Glasgow on Wednesday.
Manchester City's leading goalscorer Sergio Aguero is expected to be out for a month with a hamstring injury, the club's manager Manuel Pellegrini said on Friday.
Manchester City and Chelsea both secured their Champions League places with victories on the final day of the English Premier League season and Newcastle United joined them despite stumbling to a last-day defeat.
Liverpool's Dominik Szoboszlai struck the first telling blow in the Premier League title race with a dazzling free kick late on giving his side a 1-0 victory over rivals Arsenal.
England winger Raheem Sterling has left Chelsea by mutual agreement after being frozen out under successive managers, bringing an end to his troubled two-year spell at Stamford Bridge.
Manchester City have now won only once in 11 games in all competitions.
Manchester City coach Pep Guardiola has denied a newspaper report that he tried to sign strikers Lionel Messi and Neymar from former club Barcelona in the close season.
Manchester City were never out of the title race and the Premier League champions did not need to change their style despite a frustrating to start the season, manager Manuel Pellegrini has said.
The challenge against champions Chlesea on Sunday is for Manchester United to show that they can replicate the confident and businesslike win that City showed a month ago.
Arsenal moved to the top of the Premier League with a comfortable 3-0 win over Fulham on Saturday, extending their lead in the title race.
'The club and all of our fans will now take the time to deliver a fitting tribute and farewell to one of the greatest players to ever play in the Premier League.'
Arsenal's title hopes suffer a blow with a home defeat to Bournemouth, while Liverpool strengthens their Champions League aspirations with a win over Fulham. Brentford and Everton draw in a battle of top-five contenders.
Kai Havertz scored a late goal to give Arsenal a 1-0 victory over Sporting in the first leg of their Champions League quarter-final tie.
Everton enjoyed their first Premier League win at Manchester United for 12 years despite playing virtually the entire game with 10 men.
Saudi Arabia's Al-Hilal stunned Manchester City 4-3 in extra-time in Orlando on Monday to pull off one of the shocks of the Club World Cup.
IMAGES from Saturday's English Premier League matches.
Manchester City bounced back after conceding an early goal to beat Chelsea 3-1 on Saturday
The 44-year-old inherits a team in crisis, sitting seventh in the Premier League table -- a whopping 17 points behind leaders Arsenal -- and eliminated from both domestic cups.
Tottenham Hotspur have appointed Roberto De Zerbi as their manager on a long-term contract, the Premier League club said on Tuesday, and the Italian coach has seven games to steer the North London side to safety.
Manchester City's Matheus Nunes scored deep in injury time to salvage a crucial 2-1 Premier League victory over Aston Villa on Tuesday in their breathless chase for a Champions League berth next season.
Manchester City started their Premier League campaign in scintillating fashion on Monday with a stylish 4-0 win at home to 10-man Newcastle United that will ring alarm bells for the rest of their title rivals.
City midfielder Phil Foden was not named in England coach Thomas Tuchel's squad for a pair of upcoming games, after requesting to be omitted. Foden said this week he was nursing an ankle injury.
Manchester City came back from a goal down to beat Bournemouth 2-1 on Sunday to book their spot in the semi-finals of the FA Cup.
Manchester City went top of the Premier League after securing a controversial 2-0 win at Newcastle United on Sunday with an early Edin Dzeko goal and a stoppage time effort from Alvaro Negredo.
Real Madrid are football's biggest earners, Liverpool best in Premier League
Manchester City and Barcelona could easily have met in this season's Champions League final, Barcelona coach Gerardo Martino said on Monday when he described City as one of the "best teams in the world".
Leicester City's attempts to sign Adrien Silva from Sporting Lisbon were dealt a blow on Wednesday, with FIFA saying it had rejected an FA petition to grant the midfielder an international transfer certificate.
IMAGES from the Premier League matches played on Sunday.
The question is whether Manchester City can combine a gradual freshening up of their squad at the same time as they fight on the domestic and international front for trophies.
'Whether it was at a game far away or a tough match at Old Trafford, your support has been unshakeable. I always enjoyed meeting Manchester United fans throughout the world.'
City then comfortably closed the game out and victory in their record-extending seventh consecutive FA Cup semi-final means they will face Crystal Palace, who beat Aston Villa 3-0 on Saturday, in the final on May 17.
The Champions League play-offs are set to deliver high-octane drama as Manchester City prepare to battle European heavyweights Real Madrid, while Celtic brace for a daunting clash against Bayern Munich, with last-16 spots on the line.
Manchester City's Erling Haaland came back to haunt Borussia Dortmund with a clinical finish against his former team, while Phil Foden bagged a brilliant brace as the hosts cruised to a 4-1 win in the Champions League on Wednesday to climb to fourth.
Manchester City were sensationally knocked out of the FA Cup on Monday by third-tier Wigan Athletic who beat the 10-man Premier League leaders 1-0 in a stunning fifth round upset with a late goal by their talisman Will Grigg.